Study decodes mechanism behind severe weight loss in cancer patients
Increasing weight loss experienced by cancer patients that often leads to deaths may be caused by communication between the brain and liver, according to a study.
Nearly a third of cancer-related deaths are caused by cachexia -- a currently incurable metabolic syndrome that involves substantial weight loss, including depletion of muscle mass and body fat.
It also contributes to therapy resistance and increases mortality among affected patients.
Researchers from the Weizmann Institute of Science in Israel and the University of Texas MD Anderson Cancer Center, US, have discovered that one of the reasons for this loss is disrupted communication between the brain and the liver.
When the activity of the vagus nerve -- a major axis of brain-liver communication -- is dysregulated by cancer-tr...










