Health

Even as the bird flu virus H5N1 is evolving rapidly, with the potential to become a significant threat to human health, a team of Indian researchers using an Artificial Intelligence (AI)-based model has decoded how the deadly virus can actually spillover to humans.  In the study, published in the BMC Public Health journal, the team used BharatSim -- an ultra-large-scale agent-based simulation framework for infectious diseases that was originally built for Covid-19 modelling -- to describe the sequential stages of a zoonotic spillover. “We modelled the possibility of initial spillover events of H5N1 from birds to humans, followed by sustained human-to-human transmission,” said Philip Cherian and Gautam I. Menon from the Department of Physics at the Haryana-based Ashoka University, in the ...

While cheese -- high in saturated fat and sodium -- is known to raise the risk of high cholesterol or blood pressure, a new study has linked it to a lower risk of developing dementia.  The study, published in the journal Neurology, showed that some high-fat dairy products, such as cheddar, Brie, and Gouda, as well as whipping cream, double cream, and clotted cream, may actually lower the risk of dementia. The findings challenge some long-held assumptions about fat and brain health. However, researchers from Lund University, Sweden, clarified that “the study does not prove that eating high-fat cheese and high-fat cream lowers the risk of dementia, it only shows an association”. Researchers analysed data from 27,670 people in Sweden with an average age of 58 at the start of the study. The...

A team of researchers from Bose Institute in Kolkata has developed a peptide therapy that offers a promising, multidisciplinary approach to treating fungal keratitis -- a severe, sight-threatening infection of the cornea -- the clear front part of the eye.  The team, including researchers from the L V Prasad Eye Institute in Hyderabad, designed a 15-residue peptide, named SA-XV, derived from a larger host-defense peptide -- S100A12. This peptide, previously shown to inhibit fungal growth, has been characterised for its antifungal potency and mechanism of action. Published in the Journal of Biological Chemistry, the researchers hailed the new therapy as an alternative to antimycotics (antifungals) with reduced side effects. Corneal infections, often referred to as a slow epidemic, affect...

Researchers at the Institute of Nano Science and Technology (INST), Mohali, have identified a new pathway involving nanoparticles to treat Alzheimer’s Disease (AD), said the Ministry of Science & Technology on Tuesday.  Conventional Alzheimer’s therapies often target only a single pathological feature, such as amyloid aggregation or oxidative stress, yielding limited clinical benefit. However, the new therapy involves nanoparticles that integrate polyphenol with antioxidant properties found in green tea, a neurotransmitter, and an amino acid. It has the potential to treat Alzheimer’s Disease by changing the path of the progression of the disease, slowing it, improving memory, and supporting thinking skills, said the researchers in the paper, published in the journal Small. The ther...

Winter can feel like a natural time to slow down, but when profound fatigue, bone pain, and persistent low mood set in, it might be more than just the winter blues. This complex set of symptoms is often dismissed, yet experts warn they could be subtle indicators of one of the most widespread nutritional deficiencies: Vitamin D deficiency.  As sunlight exposure dwindles in the colder months, the body`s primary way of producing this essential nutrient is impaired, leading to consequences that affect everything from energy levels and immune function to bone health.  This winter, medical experts guide you through the latest diagnostic standards, the non-deficiency causes of fatigue, and the practical steps you can take to maximise your health and vitality throughout the winter and into the n...

A two-year-old baby boy was successfully treated by doctors in Pune after accidentally ingesting acetic acid, a corrosive household cleaning chemical that caused severe burns to his mouth, food pipe, chest, genitals and groin.  It all happened on this Children’s Day, when the two-year-old boy from Satara, met a life-threatening emergency when he accidentally ingested acetic acid, turning an ordinary day for his family into a nightmare within minutes. The corrosive liquid stored in a drinking water bottle burned his lips, oral cavity and food pipe and left painful chemical injuries on his chest and groin.  As the child gasped for breath, crying in severe pain, his frightened parents watched helplessly, unable to understand what was happening or how their playful toddler had suddenly slippe...

Doctors in Kolkata successfully carried out a highly complex microsurgical reimplantation of a completely severed right thumb of a man after he damaged it in an every day activity.  The intricate procedure was led by Dr Akhilesh Kumar Agarwal, consultant – Plastic Surgeon, at Manipal Hospital Mukundapur supported by a multidisciplinary team. Proloy Bose, a 32-year-old businessman from Subhashgram in Sonarpur, was brought to the hospital after his thumb was accidentally amputated while cleaning his motorcycle. His thumb got caught in the motorcycle’s chain cover, the protective casing over the moving chain. The injury caused severe crushing damage to the thumb, making treatment and reconstruction more difficult than a clean-cut injury. Recognising the urgency of the situation, the emerge...

The Supernova Stent -- a new and advanced brain treatment device -- has been demonstrated to be safe and effective for stroke patients, said experts at AIIMS Delhi on Saturday, who led the first clinical trial.  AIIMS Delhi was the national coordinating centre and the lead enrolling site of the GRASSROOT trial for the Supernova Stent. “This trial is a turning point for stroke treatment in India,” said Dr. Shailesh B. Gaikwad, Professor & Head, Department of Neuroimaging & Interventional Neuroradiology, AIIMS Delhi, and National Principal Investigator of the GRASSROOT Trial. “The Supernova stent has shown excellent safety and efficacy outcomes in the treatment of severe strokes, according to the preliminary trial results,” revealed the preliminary findings published in the repute...

Bringing blood glucose to normal range through lifestyle changes could halve the risk of heart attack, heart failure and premature death among prediabetics, according to a study. Findings published in `The Lancet Diabetes and Endocrinology` journal show that remission of prediabetes -- achieving normal blood glucose levels -- may establish a new, measurable target for clinical guidelines, according to researchers. A fasting blood glucose value of under 97 milligrams per decilitre proved to be a simple marker for a persistently lower risk of heart disease, regardless of age, weight, or ethnic background, the researchers said. This threshold could be applied in primary care practices worldwide, making prevention more tangible, they added. "Our results suggest that remission of prediabete...

School-going children are picking up drug and smoking habits and engaging in consumption of alcohol, with the average age of introduction to such harmful substances found to be around 13 years, suggesting a need for earlier interventions as early as primary school, a multi-city survey by AIIMS-Delhi said. The findings also showed substance use increased in higher grades, with grade XI/XII students two times more likely to report use of substances when compared with grade VIII students. This emphasised the importance of continued prevention and intervention through middle and high school. The study led by Dr Anju Dhawan of AIIMS`s National Drug Dependence Treatment Centre, published in the National Medical Journal of India this month, looks at adolescent substance use across diverse regio...