Genetic study links pregnancy stress to foetal brain defects
Stress during pregnancy such as gut changes or a trigger of the immune system can impact the brain health of the foetus, potentially paving way for neurodevelopmental abnormalities to develop, according to a new genetic study in mice.
In a paper published in the journal Nature Neuroscience, researchers have mapped how stress events during pregnancy can affect the neuroimmune landscape of the developing foetal brain using spatial transcriptomics -- they help reveal which genes of a tissue were active and where.
"Our study establishes a detailed spatial transcriptomic resource of immune gene networks during a critical window of embryonic brain development," lead researcher Brian Kalish, a physician in the division of newborn medicine at US` Boston Children`s Hospital, said.
The study mapp...










