Along with his cohorts Josephine and Rhodora, Morf digs into the personal background of this artist, whose name is Vetril Dease, and learns that he was once committed to a psychiatric hospital after murdering his own abusive father. While inside, Dease is said to have received disturbing experiments by the hospital staff, using him as a guinea pig for their untested human trials.
As Velvet Buzzsaw continues, Dease’s work seems to be cursed, as transport trucks loaded with his paintings mysteriously catch fire, gallery patrons begin to hallucinate, and the friendships of the art critics involved in bringing his work to life start falling apart.