All we know for now is that Deadpool & Wolverine are most likely a multiverse adventure that should somehow connect to the MCU continuity, but the exact mechanics behind that remain unknown for the time being. There’s some involvement from the TVA from Loki, and we can see the iconic duo jumping through one of Doctor Strange’s portals, but how everything connects to the MCU remains unclear, so one of Marvel’s Comic-Con panels is likely to mention a connection between these releases.