As Fly Me to the Moon opens, we meet Cole Davis (Tatum), the launch director at NASA in Cape Canaveral, Florida, and his deputy, Henry Smalls (Ray Romano), as Cole chases a black cat off the premises in a comical scene that focuses on the superstitions of scientists and engineers with heightened concerns over everything going right, for good reason.
Cut to a scene in a Manhattan high-rise, and we meet Kelly Jones (Johansson), a gorgeous, savvy adwoman selling the Ford Mustang with seat belts to a board room full of men. She lands her pitch, and her assistant, Ruby (Anna Garcia), marvels over Kelly’s ability to sell anything to anyone.