Mosquito saliva may boost body’s immune system against chikungunya
A team of Singaporean researchers has identified a mechanism where mosquito saliva can help boost the human body`s immune response during chikungunya virus (CHIKV) infection.
The research, published in Nature Communications, showed that sialokinin -- a bioactive peptide in Aedes mosquito saliva -- binds to neurokinin receptors on immune cells and suppresses monocyte activation.
This helps reduce inflammation and facilitates early viral dissemination. The findings offer new insight into how mosquito bites shape disease outcomes, said the team from the A*STAR Infectious Diseases Labs (A*STAR IDL) in Singapore.
"This study provides compelling evidence that mosquito salivary proteins are not just passive carriers of viruses but active modulators of host immunity," said Dr. Siew-Wai Fong, c...










