AI-powered antibiotic breakthrough offers hope for drug development
In a major advancement for tackling antibiotic resistance, researchers at The University of Texas at Austin have developed a promising new antibiotic using artificial intelligence.
The research, published in Nature Biomedical Engineering, marks a significant step forward in creating safer and more effective treatments.
The research team employed a large language model (LLM), similar to the technology behind ChatGPT, to re-engineer Protegrin-1. This potent antibiotic, naturally produced by pigs, was effective in killing bacteria but was previously too toxic for human use.
By modifying Protegrin-1, the researchers aimed to preserve its antibacterial properties while eliminating its harmful effects on human cells.
To achieve this, the team generated over 7,000 variations of Protegrin-1 th...










