Researchers identify new drug to bypass resistance in deadly childhood cancer
Researchers in Australia have identified a drug that can help overcome treatment resistance in relapsed neuroblastoma -- the deadly childhood cancer.
The discovery could improve neuroblastoma treatment -- the most common solid tumour in children outside the brain -- which currently claims nine out of 10 young patients who experience recurrence, Xinhua news agency reported
According to Australia`s Garvan Institute of Medical Research, the drug combination can bypass the cellular defences these tumours develop that lead to relapse.
The team showed that the approved lymphoma drug -- romidepsin -- triggers neuroblastoma cell death via alternative pathways, bypassing blocked routes to improve chemotherapy-resistant cases in children.
Researchers found standard chemotherapy drugs rely on th...










