Wednesday, April 29

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Researchers identify new drug to bypass resistance in deadly childhood cancer
Health

Researchers identify new drug to bypass resistance in deadly childhood cancer

Researchers in Australia have identified a drug that can help overcome treatment resistance in relapsed neuroblastoma -- the deadly childhood cancer.  The discovery could improve neuroblastoma treatment -- the most common solid tumour in children outside the brain -- which currently claims nine out of 10 young patients who experience recurrence, Xinhua news agency reported According to Australia`s Garvan Institute of Medical Research, the drug combination can bypass the cellular defences these tumours develop that lead to relapse. The team showed that the approved lymphoma drug -- romidepsin -- triggers neuroblastoma cell death via alternative pathways, bypassing blocked routes to improve chemotherapy-resistant cases in children. Researchers found standard chemotherapy drugs rely on th...
Stranger Things X review: Audience shares verdict for much-awaited series
Entertainment, Movies

Stranger Things X review: Audience shares verdict for much-awaited series

The much-anticipated sequel, Stranger Things season 5, has dropped on Netflix, after a wait of around 3 years, and netizens can`t keep calm about it. The Duffer Brothers, the creators, aim to wrap up the sci-fi horror series that debuted in 2016 with an epic finale. As Volume 1 drops, the audience has shared their reaction on X (Twitter). While some have loved it, a section is upset with the ending. Let’s check out Stranger Things 5 X reviews One netizen wrote, "damn, the end of the second episode blew my mind, fuck what an awesome series StrangerThings5 (sic)." A netizen tweeted, "I am a MASSIVE #StrangerThings fan, I’ve been watching since the beginning of time, but these duffer brothers really fucked this show. It’s corny as hell with these grown ass kids and dialogue #StrangerThings...
UNAIDS chief urges Carney to reverse planned global health funding cuts – National
Politics

UNAIDS chief urges Carney to reverse planned global health funding cuts – National

The head of the United Nations’ HIV/AIDS program is urging Prime Minister Mark Carney to reverse his government’s planned cuts to foreign aid and global health funding. “My message to Prime Minister Carney, to Canada, and to all the other donors is, stay the course,” UNAIDS executive director Winnie Byanyima told The Canadian Press on the sidelines of last week’s G20 leaders’ summit in Johannesburg.“Without global solidarity, the inequality between countries will continue to widen. We will live in a more dangerous world as these inequalities increase.”Last week, Carney announced Canada’s first-ever cut to funding for the Global Fund, a major program for fighting infectious diseases in the world’s poorest countries.The new funding pledge is 17 per cent lower than Ottawa’s last contribution ...
This Black Friday Deal Cuts the Price of AdGuard’s Family Plan to Just $16
Life Style

This Black Friday Deal Cuts the Price of AdGuard’s Family Plan to Just $16

We may earn a commission from links on this page. Deal pricing and availability subject to change after time of publication. Black Friday sales officially start Friday, November 28, and run through Cyber Monday, December 1, and Lifehacker is sharing the best sales based on product reviews, comparisons, and price-tracking tools before it's over. Follow our live blog to stay up-to-date on the best sales we find.Browse our editors’ picks for a curated list of our favorite sales on laptops, fitness tech, appliances, and more.Subscribe to our shopping newsletter, Add to Cart, for the best sales sent to your inbox.Sales are accurate at the time of publication, but prices and inventory are always subject to change. If you’re tired of websites bombarding you with ...
Navigating the mental health challenges of Indian wedding planning
Health

Navigating the mental health challenges of Indian wedding planning

The Indian wedding—a multi-day spectacle of colour, tradition, and family reunion, has by all means turned into a lavish production. From the dazzling decor to the multi-cuisine fare, every detail is significant and seemingly demands endless attention. But what happens when the pressure to deliver the `Big Fat Indian Wedding` goes beyond the budget and starts taxing the bride`s mental health?While every shaadi, as it is called India, is meant to be a joyous occasion, the reality of planning often feels more like navigating a high-stakes, social media-fuelled obstacle course. From family politics over the guest list to the paralysing pursuit of Instagram-perfect aesthetics, the modern Indian bride is often caught in a whirlwind of impossible expectations.  Experts delve into the unique men...
Study links infant RSV to higher asthma risk
Health

Study links infant RSV to higher asthma risk

An international team of scientists has found compelling evidence that early-infancy infection with respiratory syncytial virus (RSV) significantly increases the risk of developing childhood asthma.  The risk is especially higher in children with a family history of allergy or asthma. The study, published in the Science Immunology journal, suggests that protecting newborns against RSV could substantially reduce asthma cases later in life. "Childhood asthma is a complex disease with many contributing factors," said Prof. Bart Lambrecht from VIB (the Flanders Institute for Biotechnology) and Ghent University in Belgium. "We found that early-life RSV infection and genetic allergy risk interact in a very specific way that pushes the immune system toward asthma. The encouraging news is that...
The Family Man S3 Tamil dubbing goes viral, creator says team has no role
Entertainment, Movies

The Family Man S3 Tamil dubbing goes viral, creator says team has no role

The Family Man Season 3 was released on Prime Video on November 21. The popular spy thriller by Raj and DK traces the journey of TASC officer Srikant Tiwari (Manoj Bajpayee) as he balances his life as a secret agent and a common man. The series was released on the streaming platform in multiple languages. The Family Man creator on  Netizens have been having a field day with the dubbed versions of the show, originally shot in Hindi. A large portion of The Family Man 3 takes place in the North East, with Manoj Bajpayee, Priyamani, Sharib Hashmi, Jaideep Ahlawat, and Nimrat Kaur playing primary roles. Many users have been sharing amusing clips from the Tamil dubbed version. One such viral video features a heated phone call between Nimrat Kaur and Jaideep Ahlawat, where the dubbed dialogue u...
A Lifetime Subscription to Babbel Is at a Huge Discount for Black Friday
Life Style

A Lifetime Subscription to Babbel Is at a Huge Discount for Black Friday

We may earn a commission from links on this page. Deal pricing and availability subject to change after time of publication. Black Friday sales officially start Friday, November 28, and run through Cyber Monday, December 1, and Lifehacker is sharing the best sales based on product reviews, comparisons, and price-tracking tools before it's over. Follow our live blog to stay up-to-date on the best sales we find.Browse our editors’ picks for a curated list of our favorite sales on laptops, fitness tech, appliances, and more.Subscribe to our shopping newsletter, Add to Cart, for the best sales sent to your inbox.Sales are accurate at the time of publication, but prices and inventory are always subject to change. Practicing a new language can be fun, but premiu...
Canada ranks low on military oversight: study
Politics

Canada ranks low on military oversight: study

OTTAWA – Canada maintains a low level of civilian oversight of the military due to Parliament’s rigid party discipline, according to a new book that compares it with fourteen other democracies. That conclusion was arrived at after a 10-year study conducted by a trio of defence experts — academics David Auerswald, Philippe Lagassé and Stephen Saideman — and reported in a new book titled: “Overseen or Overlooked? Legislators, Armed Forces and Democratic Accountability.”“When the military makes mistakes, it can be catastrophic. So you want to have more overseers, not less,” Saideman, an international relations professor at Carleton University, told The Canadian Press.That stark conclusion comes as the federal government under Prime Minister Mark Carney prepares to embark on a massive military...
What is the B.C. oil tanker ban, and could it change under pipeline deal?
Politics

What is the B.C. oil tanker ban, and could it change under pipeline deal?

The future of the oil tanker ban in northern B.C. waters is now in question after the federal and Alberta governments signed an energy agreement Thursday that sets the stage for a pipeline to the West Coast. The memorandum of understanding (MoU) includes a commitment from Ottawa to “enable the export of bitumen from a strategic deep-water port to Asian markets, including if necessary through an appropriate adjustment to the Oil Tanker Moratorium Act.”Alberta and federal Conservatives have long argued the 2019 federal law prevents the building of new pipelines and therefore constrains the oil and gas industry, and have called for the federal government to repeal it.The B.C. government and Coastal First Nations, however, are vowing to do everything in their power to keep the tanker ban in pl...