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Study shows how virus that causes Covid-19 protects itself during replication
Health

Study shows how virus that causes Covid-19 protects itself during replication

US researchers have identified a mechanism that SARS-CoV-2 -- the virus that causes Covid-19 -- uses to protect itself inside the body as it works to replicate and infect more cells. Without this protective mechanism, viral infection is dramatically reduced, said the team from the Texas Biomedical Research Institute and the University of Chicago. The finding, published in the journal Nature Communications, not only provides a potential target for new Covid therapies but also offers insights that could inform future vaccine and antiviral development. The study builds on earlier work from Texas Biomed that identified ORF3a, a type of viral protein most important for the virus`s pathogenicity, or ability to cause disease. Specifically, the team found that SARS-CoV-2 ORF3a appears to play ...
How to Set Up and Start Using Your New Nintendo Switch 2
Life Style

How to Set Up and Start Using Your New Nintendo Switch 2

So, you’ve braved the pre-order sites, or maybe you’ve just gotten lucky while waiting in line—either way, you’ve got yourself a Nintendo Switch 2. Congratulations! But before you start gaming, there are a few things you’ll need to keep in mind while setting up your console. Nintendo is known for being user friendly, but also a bit particular. Case in point: You can only do a full transfer of your Switch 1 data to your Switch 2 during setup, and if you miss this opportunity, you’ll have to reset your device to try again, or manually copy over your games and save data piece-by-piece later on.Luckily, I’ve got your back. Read on for a quick guide on how to set up your Nintendo Switch 2, and the three other features you should set up before you start playing.How to start setting up a Nintendo...
Police retract ‘premature’ hate crime denial in Jonathan Joss shooting – National
Entertainment, Movies

Police retract ‘premature’ hate crime denial in Jonathan Joss shooting – National

San Antonio police have retracted their statement claiming there was no evidence indicating that the fatal shooting of Jonathan Joss was a hate crime, saying their initial declaration was “premature.” Joss, best known for voicing John Redcorn on animated comedy King of the Hill, was shot dead outside his home in San Antonio on Sunday. His neighbour, 56-year-old Sigfredo Alvarez Ceja, has since been arrested on a murder charge. In this handout photo released by the Bexar County Sheriff’s Office, suspect Sigfredo Ceja Alvarez poses for a booking photo on June 2, 2025 in San Antonio. He was booked on suspicion of murder of Jonathan Joss, a voice actor on the television show ‘King of the Hill.’. Bexar County Sheriff’s Office / Getty Images ...
Anil Kapoor and Vijay Varma to star in Hansal Mehta`s business drama series
Entertainment, Movies

Anil Kapoor and Vijay Varma to star in Hansal Mehta`s business drama series

What’s Hansal Mehta’s next after Gandhi, said to be his most ambitious work to date? Murmurs over the past few months suggested that in a departure from his penchant for real-life stories, the filmmaker was set to explore a business drama (New show on the cards, Feb 21). Now, mid-day has learnt that Mehta is ready to take the web series on floors in Sri Lanka this month. The Netflix offering, starring Anil Kapoor and Vijay Varma, tells the story of power, money, and morals through two business rivals whose ugly clash sends shockwaves in the financial world.  Raima Sen and Neha Dhupia also feature in the Netflix series, for which Hansal Mehta has roped in an eclectic ensemble cast Last month, Mehta apparently headed to Sri Lanka for a recce for the big-budget drama that is produced by Vik...
Will AI’s job impact be dystopian or optimistic? Maybe both, experts say – National
Politics

Will AI’s job impact be dystopian or optimistic? Maybe both, experts say – National

“A white collar bloodbath” is how Dario Amodei, CEO of leading artificial intelligence firm Anthropic, recently described the impact of artificial intelligence on the labour market to American news site Axios. On May 28, he warned that the very technology his company is creating could wipe out half of all entry-level white-collar jobs within the next five years.And he’s not alone.Micha Kaufman, CEO of Fiverr, the popular online marketplace for freelance services, shared on social media a company email from April 8 that says: “AI is coming for your jobs. Heck, it’s coming for my job too. This is a wake-up call.”He goes on to say that this will affect a variety of fields and “it doesn’t matter if you are a programmer, designer, product manager, data scientist, lawyer, customer support rep, s...
Trump wants Biden’s autopen use and ‘cognitive decline’ investigated. Why? – National
Politics

Trump wants Biden’s autopen use and ‘cognitive decline’ investigated. Why? – National

U.S. President Donald Trump has directed his administration to investigate his predecessor Joe Biden’s actions as president, including whether any orders or pardons he signed with an autopen are valid amid recent reporting that has raised questions around Biden’s “cognitive decline.” The move is the boldest yet in Trump’s campaign against his political rivals and the quest by Republicans to overturn Biden’s legacy, which has been marred by growing questions about his ability to run the country that Trump is further amplifying.Trump on Thursday called Biden’s alleged use of an autopen without his knowledge “the biggest scandal” in American political history, without providing any evidence.“It’s a very bad thing, very dangerous,” Trump said in the Oval Office, arguing that, “essentially, who...
Legault says focus is on economy as legislative session ends and his party trails in the polls
Politics

Legault says focus is on economy as legislative session ends and his party trails in the polls

By Staff The Canadian Press Posted June 6, 2025 2:54 pm Updated June 6, 2025 3:01 pm 1 min read Descrease article font size Increase article font size Quebec Premier François Legault says the economy is his top priority as the provincial legislature rises for the summer. Legault says he wants to see new projects launched across Quebec in the face of U.S. President Donald Trump’s economic threats, including in the mining sector. Get breaking National news For news ...
Study links early periods, later menopause to slower brain ageing in women
Health

Study links early periods, later menopause to slower brain ageing in women

Women with early onset of periods, and later menopause -- which means a longer reproductive span -- can have a healthier brain ageing in life, according to a study. The study showed how a woman’s reproductive years may shape brain health later in life and also reduce the risk of dementia. It also suggested the role of oestradiol (or the lack thereof) in the development of dementia. Oestradiol levels rise at puberty, remain high during most of a woman’s reproductive life, and then decline sharply around menopause. This drop in oestradiol has been linked to an increased risk of dementia and other age-related brain conditions. “These findings support the idea that oestradiol -- the most potent and prevalent form of oestrogen during a woman’s reproductive years -- may help protect the brai...
Canada, China to regularize communication after Carney, Li talks – National
Politics

Canada, China to regularize communication after Carney, Li talks – National

By Staff The Canadian Press Posted June 6, 2025 7:17 am 1 min read Descrease article font size Increase article font size Prime Minister Mark Carney and Chinese Premier Li Qiang have agreed to regularize channels of communication between the two countries. A readout from Carney’s office also says the leaders committed to working together to address the fentanyl crisis. Get breaking National news For news impacting Canada and around the world, sign up for breaking news alerts delivered directly to you when they happen. Canada and China have been involved in a trade di...
Why an Apple TV Box Is More Private Than Your Smart TV (but Not Perfect)
Life Style

Why an Apple TV Box Is More Private Than Your Smart TV (but Not Perfect)

We may earn a commission from links on this page. Let's be clear: smart TVs are a privacy nightmare. Almost all of them keep track of everything you watch, even when you're using an HDMI cable, and send it off to analytics firms, advertisers, and who knows who else. In capitalist America, TV watches you.A common piece of privacy advice, given this, is to disconnect your smart TV from the internet and use an Apple TV to do your streaming instead. And there is merit to this advice: Apple's streaming box collects far less private information than a standard smart TV while still providing a straightforward, remote-based user interface with support for all the major streaming services.Having said that, it's not as though Apple collects no data. And using an Apple TV means buyin...